Hot Topics: Muscle Invasive Bladder Cancer: Entering an Era of New Therapies and Improved Outcomes

Saturday, November 1, 2025

14:00 - 15:30 GMT+0

Co-Chair(s)

Param Mariappan

Professor, Consultant Urological Surgeon
The University of Edinburgh, United Kingdom
Piyush Agarwal

Professor of Surgery and Urology, Director of Bladder Cancer Program and Fellowship in Urologic Oncology
University of Chicago, United States

At the end of this session, attendees should be able to:

Evaluate the role of imaging and biomarkers in assessing response to neoadjuvant therapy for muscle-invasive bladder cancer (MIBC).
Analyze functional outcomes and postoperative considerations of open and robotic neobladder reconstruction with respect to patient recovery, continence, and quality of life.
Recognize the role of urologists in optimizing long-term cancer control through bladder preservation strategies.
Examine evolving approaches for neoadjuvant and adjuvant therapies for MIBC and their implications for clinical decision-making.

14:00 - 14:12 GMT+0

Imaging and Biomarkers for Assessing Response to Neoadjuvant Therapy
Speaker: Roberto Contieri – Istituto Nazionale Tumori IRCCS Fondazione G. Pascale
14:10 - 14:24 GMT+0

Functional Outcomes Neobladder Open vs Robotic Including Post-Operative Management
Speaker: Hammad Ather – Pakistan
14:24 - 14:39 GMT+0

Urologist Role In Bladder Preservation - Optimizing Local Control for Long Term Cancer Control
Speaker: Adam S. Feldman – Massachusetts General Hospital
14:39 - 14:50 GMT+0

What Is the New Standard for Neoadjuvant Therapy?
Speaker: Shilpa Gupta – Cleveland Clinic
14:50 - 15:00 GMT+0

Adjuvant Radiotherapy - A New Standard?
Speaker: YeePei Song – The Christie Hospital NHS Foundation Trust
15:00 - 15:30 GMT+0

Cases and Discussion
Speaker: Piyush K. Agarwal – University of Chicago